PATENTS IN MOLECULAR DIVERSITY

This list is arranged by the name of the first author. Please, note the change in numbering of the references. Any omissions, mistakes and inconsistencies please communicate to the authors of compilation (michal@5z.com). (If you are pointing to any reference, please use its ID# -- the last number in the reference.) You are welcome to use this compilation in your work. Proper way to quote it in your paper is: Lebl M., Leblova Z.: Dynamic database of references in molecular diversity. Internet http://www.5z.com.

Recently added entries are marked in bold

1. Akporiaye,D.E., Karlsson,A., Dahl,I.M., & Wendelbo,R. (2003) Norway. Multiple parallel processing assembly. US. 20030206830. 2003-426086, 12 p. #19006

2. Baldwin,J.J., Dolle,R.E., III, Dillard,L.W., & Guo,J. (2003) Pharmacopeia Inc. Chemically inert molecular tags. WO. 2003093823. 2003-US12325, 22 p. #19169

3. Bartholomew,B.A., Latif,Z., & Bright,S.G. (2003) Molecularnature Limited. Process for scavenging phytochemicals. WO. 2003074144. 2003-GB880, 32 p. #19028

4. Basset,J.m., Coperet,C., Maunders,B.M., Rataboul,F., Saggio,G., Soulivong,D., Taoufik,M., & Thivolle-cazat,J. (2003) Bp Chemicals Limited. Supported metal compound, preparation of the compound and use of the compound as a catalyst. WO. 2003061823. 2003-GB173, 45 p. #19218

5. Betley,J.R. (2003) Adprotech Limited. Synthesis and use of pseudo-cysteine for native chemical ligation. WO. 2003080650. 2003-GB1270, 29 p. #19188

6. Blum,H., Buetfering,L., Kraemer,R., Mueller,H., & Sabela,E. (2003) G.Henkel Kommanditgesellschaft Auf Aktien. Device and method for simultaneously testing the action of liquids on surface structures, and use of said device. WO. 2003069322. 2003-EP1156, 21 p. #19034

7. Carlson,R.E. (2003) U.S.A.Receptors LLC. Artificial receptors, building blocks, and methods. WO. 2003074990. 2003-US5328, 145 p. #19023

8. Cassells,N.P. (2003) LGC Limited. Apparatus and method for biochemical analysis. WO. 2003087293. 2003-GB1453, 42 p. #19011

9. Chen,J. (2003) U.The Procter & Gamble Company. Process for preparing alpha-hydroxyamides and alpha-ketoamides on a solid phase support. US. 2003176739. 2003-335782, 9 p. #19194

10. Climie,S., Desouza,L.V., Duewel,H., Hosfield,C.M., Liao,L.C.-L., McBroom,L.D.B., Sucholeiki,I., & Toledo-Sherman,L.M. (2003) MDS Proteomics Inc. Chemical proteomics. US. 2003166007. 2003-358119, 35 p. #19030

11. Cook,W.D., & Mccaw,B.J. (2003) A.The Walter and Eliza Hall Institute of Medical Research. Protein and nucleotide sequences of Lmt tumor suppressor gene of mouse and human. WO. 2003066869. 2003-AU126, 373 p. #19037

12. Curran,D.P., Parniak,M.A., Gabarda,A., Zhang,W., Luo,Z., & Hiu-tung,C.C. (2003) U.University of Pittsburgh & Fluorous Techonologies Inc. Preparation of mappicine analogs and intermediates thereof for their therapeutic use as antiviral agents. WO. 2003074524. 2003-US6442, 115 p. #19025

13. Darvas,F., Uerge,L., Bucsai,A., Beres,M., Dorman,G., Krajcsi,P., Godorhazy,L., Bagyi,I., Puskas,L., Hackler,L., & Zvara,A. (2003) R.Comgenex & B.K.MTA Szegedi. New active solid support and method for surface immobilization of combinatorial compounds or libraries. WO. 2003083477. 2003-HU25, 23 p. #19015

14. Devadas,B., Walker,J., Selness,S.R., Boehm,T.L., Durley,R.C., Devraj,R., Hickory,B.S., Rucker,P.V., Jerome,K.D., Madsen,H.M., Alvira,E., Promo,M.A., Blevis-Bal,R.M., Marrufo,L.D., Hitchcock,J., Owen,T., Naing,W., Xing,L., Shieh,H.S., Sambandam,A., Liu,S., Scott,I.L., & McGee,K.F. (2003) Pharmacia Corporation. Preparation of substituted pyridinones as modulators of p38 MAP kinase. WO. 2003068230. 2003-US4634, 1052 p. #19204

15. Evans,D.J., Simpkin,D.S.A., Wellings,D.A., & Atherton,E. (2003) Avecia Limited. Process for the synthesis of peptides. WO. 2003093302. 2003-GB1949, 21 p. #19170

16. Ferguson,I.A., & Tani,H. (2003) Australia. Non-invasive delivery of polypeptides through the blood-brain barrier, and in vivo selection of endocytotic ligands. WO. 2003091387. 2003-IB2371, 174 p. #19004

17. Fischer,A., Hiemisch,H., Williams,S., Brenner,S., Walker,R., Vermaas,E., & Fu,R. (2003) I.Lynx Therapeutics. Generating nucleic acid libraries of same-length signature sequences for massively parallel signature sequencing. WO. 2003091416. 2003-US13076, 54 p. #19173

18. Forood,B.B., & Lebl,M. (2003) I.Illumina. Sensor arrays for detecting analytes in fluids. US. 2003198573. 2003-352779, 23 p. #19013

19. Ganan Calvo,A.M., Chavez De Diego,S., & Cebolla Ramirez,A. (2003) S.Universidad De Sevilla. Arrays of capillary tubes for chemical and biological use. WO. 2003066217. 2003-ES66, 33 p. #19038

20. Garcia-Echeverria,C. (2003) A.-G.Novartis & P.G.Novartis. .beta.-homolysine conjugates and their use as transport enhancer. WO. 2003063910. 2003-EP803, 32 p. #19212

21. Gascoyne,P.R.C., Vykoukal,D., & Becker,F.F. (2003) t.U.o.T.S.U.Board of Regents. Methods and apparatus for solid-phase oligonucleotide synthesis. WO. 2003057924. 2003-US180, 48 p. #19224

22. Gascoyne,P.R.C., Vykoukal,J.V., Schwartz,J., & Becker,F.F. (2003) t.U.o.T.S.U.Board of Regents. Droplet-based micro-fluidic oligonucleotide synthesis engine. WO. 2003057010. 2003-US183, 38 p. #19225

23. Gramatikova,S., Hazlewood,G., Lam,D., & Barton,N. (2003) Diversa Corporation. Identification, cloning and sequences of phospholipases from environmental sources and their use in oil degumming and other industrial methods. WO. 2003089620. 2003-US12556, 281 p. #19007

24. Groarke,M. (2003) P.L.C.Johnson Matthey. Solid phase peptide synthesis on silica. WO. 2003068806. 2003-GB513, 26 p. #19203

25. Herwig,J., Richter,R., Roos,M., & Oenbrink,G. (2003) A.-G.Degussa. Work-up of residues in the oxidative preparation of dicarboxylic acids. US. 2003195374. 2003-411277, 5 p. #19183

26. Irving,E., Brown,S., Turner,N.J., Flitsch,S.L., & Lins,R. (2003) UFC Limited. Method of producing dynamic combinatorial libraries through the enzyme-catalysed reactions. WO. 2003086612. 2003-GB1615, 27 p. #19012

27. Kato,S., & Fujimori,F. (2003) J.Japan Science and Technology Corporation & Japan as Represented by Director General of National Rehabilitation Center for the Disabled. Expression of fusion protein comprising fluoresce protein and targeting signal peptide for cell screening. WO. 2003083112. 2003-JP4180, 40 p. #19184

28. Kozmin,S.A., & Wang,Y. (2003) U.University of Chicago. Device and method for multiparallel synthesis and screening of a chemical library. US. 2003170733. 2003-358074, 26 p. #19029

29. Latif,Z., Sharp,H.J., & Robinson,N. (2003) Molecularnature Limited. Process for extracting non-polar phytochemicals. WO. 2003074145. 2003-GB892, 37 p. #19027

30. Lynn,D., & Li,X. (2003) U.Emory University. Template-driven polymerization processes for synthesis of DNA and polymers and components related to such processes. WO. 2003082901. 2003-US9230, 39 p. #19185

31. Menges,M., Puhl,M., Rentzea,C., Harreus,A., Bussche-Huennefeld,C.V.D., Gypser,A., Schwoegler,A., Witschel,M., Zagar,C., Grossmann,K., Schiffer,H., & Roehl,F. (2003) G.BASF Aktiengesellschaft. Synthesis of phenylalanine derivatives for use as herbicides. WO. 2003066576. 2003-EP926, 162 p. #19209

32. Merutka,G., Zhu,Z., & Almeda,S.A. (2003) I.Intrabiotics Pharmaceuticals. Hybrid synthetic method for antimicrobial peptides. WO. 2003062266. 2003-US1998, 70 p. #19216

33. Meutermans,W., West,M.L., Adamson,G., Thanh Le,G., Drinnan,N.B., Abbenante,G., Becker,B., Grathwohl,M., Rajaratnam,P., & Tometzki,G. (2003) Alchemia Pty.Ltd. Combinatorial library solid phase synthesis of disaccharides for drug discovery. WO. 2003093286. 2003-AU494, 156 p. #19171

34. Migawa,M.T., Swayze,E.E., & Griffey,R.H. (2003) I.Isis Pharmaceuticals. Preparation of pyranosyl cytosine nucleosides as antibacterial and antifungal agents and inhibitors of protein translation. WO. 2003066633. 2003-US3191, 72 p. #19207

35. Minamitake,Y., Matsumoto,M., & Makino,T. (2003) L.J.Daiichi Suntory Pharma Co. & K.Kangawa. Optimization of the solid-phase segment condensation approach for peptide chemical synthesis with quaternary ammonium fluoride side chain deprotection. WO. 2003084983. 2003-JP4590, 120 p. #19181

36. Moody,D.J., Wellings,D.A., & McCormac,P. (2003) Avecia Limited. Process for preparing oligonucleotides. WO. 2003091267. 2003-GB1795, 28 p. #19174

37. Nagy,Z., & Brandstetter,T. (2003) G.GPC Biotech AG. Preparation of peptides as immunosuppressants. WO. 2003082197. 2003-US9219, 129 p. #19186

38. Parker,H.Y., & Mulligan,J.T. (2003) I.Blue Heron Biotechnology. Solid phase synthesis methods for polynucleotide gene fragment production. WO. 2003085094. 2003-US9814, 102 p. #19179

39. Pauluth,D., Kirsch,P., Baeuerle,P., & Deeg,O. (2003) Merck Patent. Preparation of quaterphenyls and related compounds via combinatorial chemistry for use as liquid crystals. EP. 1346995. 2003-3811, 48 p. #19018

40. Pecharsky,V.K., Balema,V.P., Wiench,J.W., & Pruski,M. (2003) I.U.Iowa State University Research Foundation. Solvent-free mechanochemical preparation of phosphonium salts, phosphorus ylides, and olefins by Wittig and related reactions. WO. 2003066548. 2003-US3458, 38 p. #19210

41. Pieken,W., Wolter,A., & Leuck,M. (2003) L.Proligo. Novel diene capping reagents for the integrated synthesis and purification of oligonucleotides with increased yields and efficient removal of failure sequences. WO. 2003062452. 2003-US2008, 46 p. #19215

42. Pinel,A.M. (2003) Fr.Institut Europeen de Biologie Cellulaire. Preparation of novel peptide derivatives and their therapeutic and cosmetic application. WO. 2003064458. 2003-FR300, 27 p. #19211

43. Prokai,L. (2003) U.University of Florida. Preparation of peptide antagonists of RF-amide neuropeptides. WO. 2003084303. 2003-US8820, 22 p. #19182

44. Rademann,J. (2003) Germany. Terephthalaldehyde-crosslinked polyethyleneimine as swellable support for solid phase synthesis. WO. 2003085031. 2003-EP3699, 32 p. #19180

45. Sessler,J.L., Seidel,D., Bolze,F.R., & Koehler,T. (2003) t.U.o.T.S.U.Board of Regents. Method for the preparation of cyclo[n]pyrroles via an oxidative coupling procedure. WO. 2003072581. 2003-US6114, 91 p. #19199

46. Shinoki,H., Nirasawa,M., & Sudo,Y. (2003) L.J.Fuji Photo Film Co. Arrays containing glass coated with vinylsulfonyl compounds for detection of DNA. EP. 1348482. 2003-6741, 3 p. #19192

47. Spivey,A.C., Turner,D.J., Cupertino,D.C., Mackie,P.R., Anemian,R.M., & Yeates,S.G. (2003) Avecia Limited. Preparation of conjugated molecules and materials for use therein via germanium linker containing Suzuki coupling reaction. WO. 2003089499. 2003-GB1664, 70 p. #19175

48. Staehle,W., Schadt,O., Jonczyk,A., & Goodman,S. (2003) Merck Patent. Preparation of 3-biphenylpropionic acids as .alpha.v.beta.6-integrin receptor inhibitors. WO. 2003066594. 2003-EP327, 71 p. #19208

49. Steiner,U., Woell,D., & Walbert,S. (2003) G.Universitaet Konstanz. A method for cleavage of labile functional groups from chemical compounds. WO. 2003074542. 2003-EP2208, 35 p. #19024

50. Strong,A.E. (2003) S.A.RMF Dictagene. Solid phase synthesis of .alpha.-interferons. WO. 2003070764. 2003-EP1745, 47 p. #19202

51. Tadayoni-Rebek,M., Amshey,J.W., & Rooney,R. (2003) Invitrogen Corporation. Highly homogeneous defined sequence, labeled standards for 1- and 2-dimensional gel electrophoresis. WO. 2003070967. 2003-US4814, 88 p. #19201

52. Van Erden,L., & Chandler,W.H. (2003) I.Symyx Technologies. High pressure parallel reactor with individually isolatable vessels. US. 2003161763. 2003-348220, 27 p. #19033

53. Wallach,D., Ramakrishnan,P., & Shmushkovich,T. (2003) I.Yeda Research and Development Co.Ltd. Modulation of NIK with IL-2 common .gamma. chain and therapeutic uses thereof. WO. 2003087380. 2003-IL317, 98 p. #19010

54. Watson,A.A., & Nash,R.J. (2003) Molecularnature Limited. Process for extracting polar phytochemicals. WO. 2003074146. 2003-GB905, 35 p. #19026

55. Wiesner,M., Goodman,S., Kessler,H., Thumshirn,G., Weber,D., & Gottschling,D. (2003) G.Merck Patent GmbH. Solid phase preparation of isoquinolines as integrin inhibitors for the prevention of coronary heart diseases. WO. 2003074512. 2003-EP1248, 66 p. #19197

56. Anonymous. (2002) U.S.A.Albany Medical College & D.R.Crawford. Calcineurin modulators. WO. 2003006619. 2002-US22122, 104 p. #19114

57. Albericio Palomera,F., Caba Naudi,J.M., Giralt Lledo,E., Manzanares,I., & Rodriguez,I. (2002) S.A.Pharma Mar & G.K.Ruffles. Process for producing trunkamide A compounds. WO. 0281506. 2002-GB1527, 51 p. #18205

58. Albert,J., Mayer,G., Schober,A., & Gross,A. (2002) E.V.Institut fuer Physikalische Hochtechnologie. Microtiter plate for parallel microsyntheses, especially at high temperatures. WO. 2003055589. 2002-EP14763, 17 p. #19048

59. Aldrich,J.V., & Kumar,V. (2002) USA. Methods of synthesizing and using derivatives of [2-(2-aminoethoxy)ethoxy]acetic acid. US. 2003134989. 2002-308672, 14 p. #19226

60. Alexander,J.N., IV, Piccolini,R.J., Gore,R.H., Cruz,C.A., Jiang,B., Lundquist,E.G., Bortnick,N.M., Barrett,J.H., & Machleder,W.H. (2002) U.Rohm and Haas Company. Polymeric nanoparticles for improved solid media. EP. 1245276. 2002-252206, 16 p. #17861

61. Amici,R., D'Anello,M., Martina,K., Salom,B., & Vulpetti,A. (2002) S.P.A.Pharmacia Italia. Aminoindazole derivatives active as kinase inhibitors, process for their preparation and pharmaceutical compositions containing them. WO. 2003028720. 2002-EP10534, 132 p. #19079

62. An,H., Gunic,E., Koh,Y.H., Chen,H., Barawkar,D., Zhang,W., Girardet,J.l., Rong,F., & Hong,Z. (2002) Ribapharm Inc. Solid phase combinatorial synthesis of substituted purine nucleoside libraries as potential antiviral and antitumor agents. WO. 2003051881. 2002-US40414, 113 p. #19238

63. An,H., Girardet,J.l., Ramasamy,K., Ding,Y., & Hong,Z. (2002) Ribapharm Inc. Solid phase synthesis and combinatorial library of nucleoside analogs useful as antiviral agents. WO. 2003051897. 2002-US40365, 45 p. #19236

64. An,H., Chamakura,V., Chen,H., & Hong,Z. (2002) Ribapharm Inc. Solid phase synthesis and combinatorial library of nucleosides as potential antiviral and anticancer agents. WO. 2003051898. 2002-US40415, 130 p. #19235

65. An,H., Girardet,J.l., Ding,Y., Barawkar,D., & Hong,Z. (2002) Ribapharm Inc. Solid-phase synthesis and combinatorial libraries of cytidine nucleosides useful as antitumor and antiviral agents. WO. 2003051896. 2002-US35558, 99 p. #19237

66. An,H., Hong,Z., Smith,K., Ding,Y., & Girardet,J.l. (2002) Ribapharm Inc. Tricyclic nucleoside derivatives for use as antiviral agents. WO. 2003061385. 2002-US31369, 65 p. #19044

67. Backes,B.J., & Harris,J.L. (2002) L.L.C.IRM. Construction of combinatorial libraries of protease fluorogenic substrates and application to substrate profile determination. US. 2003059847. 2002-229950, 26 p. #19275

68. Baig,S. (2002) I.U.The University of Georgia Research Foundation. Identification of peptide active site inhibitors of proteases and other scission enzymes and application to drug design. WO. 0286115. 2002-US12611, 174 p. #17848

69. Baker,M.J., Johnston,P., & Murphy,D. (2002) Bp Chemicals Limited & P.L.C.Johnson Matthey. Process for the preparation of a metal-impregnated microspheroidal catalyst. WO. 2003061829. 2002-GB5761, 23 p. #19217

70. Battersby,B.J., Miller,C.R., Trau,M., Way,J.C., & Johnston,A. (2002) Australia. Device and methods for directed synthesis of chemical libraries. US. 2003182068. 2002-283741, 94 p. #19017

71. Beaucage,S.L., Grajkowski,A., & Wilk,A. (2002) U.Department of Health and Human Services. Thermolabile hydroxyl protecting groups in solid phase synthesis of nucleosides. WO. 2003048179. 2002-US38400, 39 p. #19244

72. Beier,M., & Stahler,C.F. (2002) A.-G.Febit. Methods and apparatuses for electronic determination of analytes. US. 2002160427. 2002-132167, 14 p. #18194

73. Beigelman,L., Azhayev,A., & Azhayeva,E. (2002) I.Ribozyme Pharmacuticals. Enzymatic nucleic acid peptide conjugates. WO. 2003008628. 2002-US23324, 88 p. #19295

74. Berkowitz,D.B., Bose,M., & Choi,S. (2002) U.University of Nebraska. Biphasic process for in situ enzymatic screening to optimize variables in organic reactions. US. 2003148257. 2002-235950, 47 p. #19042

75. Berta,D., Felder,E., Vulpetti,A., & Villa,M. (2002) I.S.Pharmacia. Oxazolyl-pyrazole derivatives as protein kinase inhibitors, their preparation and combinatorial libraries, and their pharmaceutical use in the treatment of cancer and other diseases and disorders. WO. 0262804. 2002-EP995, 107 p. #17876

76. Besenbruch,R., Frank,M., Maier,S., Metz,G., Ottleben,H., Rau,H., Sekul,R., & Vetter,D. (2002) D.G.Graffinity Pharmaceutical. Low affinity screening method. WO. 0263299. 2002-EP1184, 75 p. #17875

77. Bianchi,D., D'Aloisio,R., & Tassinari,R. (2002) E.S.Polimeri. Preparation of hydroxylated aromatic compounds. WO. 2003042146. 2002-EP12169, 26 p. #19252

78. Bleckmann,A., Kroepke,R., & Riedel,H. (2002) A.-G.Beiersdorf. Self-foaming or mousse-type preparations comprising organic hydrocolloids and particulate hydrophobic and/or hydrophobed and/or oil-absorbing solid substances. WO. 0274264. 2002-EP2826, 76 p. #18236

79. Boteju,L.W., Konkel,M.J., Kawakami,J.K., & Wetzel,J. (2002) USA. Preparation of N-sulfonyl dipeptides specific for NPFF receptors. US. 2003144310. 2002-253288, 41 p. #19220

80. Botfield,M., Mcdonald,F., Kraetzschmar,J., Lindenthal,B., & Kreft,B. (2002) Vertex Pharmaceuticals Incorporated. Heterocyclic compounds, and preparation thereof, for modulators of the cholesterol biosynthetic pathway, and therapeutic use. WO. 2003037338. 2002-US35269, 225 p. #19068

81. Braisted,A.C., Erlanson,D.A., & Jacobs,J.W. (2002) USA. Novel ligands and libraries of ligands. US. 2003013125. 2002-143455, 73 p. #19115

82. Breitling,F. (2002) Germany. High-resolution arrays for combinatorial synthesis. WO. 2003008088. 2002-DE2622, 62 p. #19112

83. Bruce,I., Davies,M., & Wolter,A. (2002) U.S.A.Proligo LLC. Synthesis of oligonucleotides probes and their use in detection of nucleic acids and microarrays. WO. 2003043402. 2002-US33699, 110 p. #19248

84. Campian,E., Lou,B., & Mjalli,A.M.M. (2002) USA. Method for the synthesis of .alpha.-sulfonamido amide, carboxylic acid and hydroxamic acid derivatives. US. 2003013910. 2002-146713, 17 p. #19300

85. Cardozo,M.G., Graham,E.T., & Jacober,S.P. (2002) USA. A Novel Frequency Distribution Selection Method for Efficient Plate Layout of a Diverse Combinatorial Library. US. 2002127608. 2002-43707, 27 p. #17866

86. Cavicchioli,M., Pevarello,P., Salom,B., & Vulpetti,A. (2002) I.S.Pharmacia. Preparation of aminoisoxazoles as protein kinase inhibitors for treatment of cancer and other proliferative diseases. WO. 2003013517. 2002-EP8634, 253 p. #19292

87. Cawse,J.N. (2002) U.General Electric Company. Mixture experiment design method and system. US. 2003153095. 2002-36227, 22 p. #19040

88. Cereda,E., Pellegrini,C.M., Quai,M., & Barbaglia,W. (2002) P.K.G.Boehringer Ingelheim. Polymers based on N-carbamyl-N'-dimethylsilyl methyl-piperazine traceless linkers for the solid phase synthesis of phenyl-based libraries. WO. 0260960. 2002-EP312, 25 p. #18286

89. Chang,Y.T., Moon,H.S., & Khersonsky,S.M. (2002) U.New York University. Combinatorial preparation of triazine library with linkers, for use as universal small-molecule chips for chemical genetics, functional proteomics, and sensors. WO. 2003050237. 2002-US32096, 34 p. #19059

90. Chen,J. (2002) U.The Procter & Gamble Company. Process for preparing 3-(acylamino)imidazo[1,2-a]pyridines using an isonitrile resin. US. 2003144518. 2002-302246, 9 p. #19219

91. Chen,S., Luo,Y., Chen,A.C., Nikiforov,T., Xiao,J., & Nguyen,Q. (2002) I.Genospectra. Biochemical analysis system with combinatorial chemistry applications. WO. 2003042697. 2002-US36838, 158 p. #19066

92. Chen,Y.F. (2002) T.Scinopharm Singapore. Process for synthesizing peptides by using a PEG polymer support. US. 2003078372. 2002-247429, 3 p. #19262

93. Clancy,M.J.A., Clumming,K.L., & McCrystal,C.B. (2002) Elan Corporation. Delivery of a bioactive material. WO. 2003003999. 2002-IB3651, 37 p. #19303

94. Coffen,D.L., Xiao,X.y., & Hu,Y. (2002) USA. Method for tracking compounds in solution-phase combinatorial chemistry. US. 2002098598. 2002-56257, 9 p. #17882

95. Colarusso,S., Gardelli,C., Gerlach,B., Harper,S., Koch,U., Matassa,V.G., Muraglia,E., Narjes,F., Ontoria,O.J.M., Petrocchi,A., Ponzi,S., Stansfield,I., & Summa,V. (2002) Istituto di Ricerche di Biologia Molecolare. Preparation of peptide inhibitors of hepatitis C virus NS3 protease. WO. 0279234. 2002-EP3435, 151 p. #18214

96. Combs,A.P. (2002) USA. Novel chemical combinatorial library synthesis particles. US. 2003044850. 2002-229859, 5 p. #19095

97. Cooper,J., & Johannessen,E.A. (2002) UK.University Court of the University of Glasgow. Thermoelectric sensor. WO. 2003048709. 2002-GB5572, 47 p. #19060

98. Coy,D.H., & Rajeswaran,W.G. (2002) U.The Administrators of the Tulane Educational Fund. Preparation of cyclic peptides as somatostatin agonists. WO. 0281499. 2002-US10882, 43 p. #18206

99. Curley,R.W., Jr., Mershon,S.M., Barnett,D.W., Clagett-Dame,M., & Chapman,J.S. (2002) U.The Ohio State University Research Foundation. Solid phase synthesis of arylretinamides for their therapeutic use as anticancer agents. WO. 2003003987. 2002-US21452, 51 p. #19304

100. Curran,D.P., & Dandapani,S. (2002) U.University of Pittsburgh. Fluorous nucleophilic substitution of alcohols and reagents for use therein, specifically, perfluoroalkyl-containing phosphines and azodicarboxylates as polyfluorinated reagents for the Mitsunobu reaction. WO. 2003016246. 2002-US26045, 51 p. #19102

101. Deadman,J.J., Spencer,J., Greenidge,P.A., Goodwin,C.A., Kakkar,V.V., & Scully,M.F. (2002) Trigen Limited. Preparation of serine protease inhibitors comprising a non-peptide boronate or other hydrogen-bond acceptor. WO. 0257273. 2002-GB224, 117 p. #18294

102. Deprez,P., & Patek,M. (2002) S.A.Aventis Pharma. Novel urea derivatives for use as calcium receptor agonists. WO. 0259102. 2002-FR279, 96 p. #18291

103. Dialynas,D., Scalia,A., Lucas,J., & Briggs,K. (2002) S.A.Genset. RYZN and TNF receptor superfamily related proteins for treatment of metabolic disorders and screening of agonists and antagonists. WO. 2003045421. 2002-IB4581, 37 p. #19063

104. Ding,S., Ding,Q., Gray,N.S., & Schultz,P.G. (2002) B.IRM LLC. Methods for the synthesis of substituted purines. WO. 2003031405. 2002-US32679, 79 p. #19264

105. Ding,S., Ding,Q., & Gray,N.S. (2002) B.IRM LLC. C2-, C6- and 9-Aryl-substituted purine and other heteroaryl kinase inhibitor scaffolds and methods for their preparation. WO. 2003031406. 2002-US32680, 68 p. #19077

106. Doerwald,F.Z., Andersen,K.E., & Sorensen,J.L. (2002) N.A.Novo & I.Boehringer, I. Preparation of substituted piperazines and diazepanes as histamine H3 receptor agonists. WO. 2003004480. 2002-DK438, 182 p. #19302

107. Domany,G., Horvath,C., Farkas,S., Barta Szalai,G., Nagy,J., Kolok,S., Kovacs Bozo,E., Borza,I., Vago,I., Bielik,A., Szendrei,M., & Keseru,G. (2002) H.Richter Gedeon Vegyeszeti Gyar Rt., G.Bartane Szalai, & E.Kovacsne Bozo. Preparation of 2-(piperidin-1-yl)acetamides as NMDA receptor antagonists. WO. 2003010159. 2002-HU71, 132 p. #19294

108. Dordick,J.S., Santhanan,L., Hogg,M.G., & Holland,J.A. (2002) Rensselaer Polytechnic Institute & United States Department of Veterans Affairs. Solid-phase, array-based biocatalytic manufacture of oligophenols. WO. 2003037829. 2002-US35280, 49 p. #19257

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